Chinese Pottery Essay Example For Students

Chinese Pottery Essay The earliest Chinese pottery of which we have any records is the Neolithic ware from the river plains and loess highlands of north and north-west China. It was made between 5000 and 2000 B.C. and contains bowls, jars, pots and beakers of low-fires earthenware. This pots were not turned on a wheel but were buildt up by what is known as the Coil Method. That is, a long sausage of clay was wound carefully up into a coil shape and this coil was smoothed and patted by hand into the shape of a pot. During the Tang Dynasty China became the greatest and most widespread empire in the world . Tang pottery is powerful and lively with sweeping sinuous curves while its decoration is often made up of flamboyant shapes and contrasting colours. The first hundred and thirty years of the Tang Dynasty made up one of the most glorious periods of Chinese history. During this time the dynasty was blessed with three rulers of supreme ability: Li Shih-Min, known as the Emperor Tang Tai Tsung, the real founder of the dynasty, who is often spoken of as the greatest of all Chinese emperors; the Empress Wu fought her way to the throne with bloodthirsty ruthlessness and yet brought twenty years of peace and prosperity to the empire; and the lastly Tang Ming Huang who brought the empire to the peak of its prosperity and cultural splendour, and then, alas, in the foolishness of his old age saw the whole splendid fabric torn to shades. During these hundred and thirty years not only did agriculture prosper, especially in the rice-growing lands of central and southern China, but arts and handicrafts were flourishing. Szechnan Province produced gold and silverwares and fine brocades, while porcelain of the highest quality was made in several centres. Plate I Silver wine globet. Tand Dynasty. Victoria and Albert Museum, London. During the tang Dynasty the Chinese were brought into close contact with the civilizations of India. The Middle East and central Asia, and their art forms were influenced and greatly enriched by these contacts. From the Sassanid empire, in what is now Persia, came a form of finely wrought metalwork which made use of delicately incised designs of flowers, animals and curving lines. This silver piece is good example of the Chinese adaption of the Sassanian style. Plate II Horse in glazed pottery. Grave figure. Tang Dynasty. British Museum, London. Plate III Tang Dynasty. British Museum, London. This plate was found at Tunhaung, and is probably a tenth-century copy of an earlier Tang original. Kuan Yin originated in India as a male god named Avolokitesvara, and early pictures such as this one show the god wearing moustache; but in the course of time the Chinese came to think of Kuan Yin as a goddess.

Dont Talk To Cops Essays (538 words) - Arrest, Criminal Law

Don't Talk to Cops By Robert W. Zeuner, Member of the New York State Bar " GOOD MORNING! My name is investigator Holmes. Do you mind answering a few simple questions?" If you open your door one day and are greeted with those words, STOP AND THINK! Whether it is the local police or the FBI at your door, you have certain legal rights of which you ought to be aware before you proceed any further. In the first place, when law enforcement authorities come to see you, there are no "simple questions". Unless they are investigating a traffic accident, you can be sure that they want information about somebody. And that somebody may be you! Rule number one to remember when confronted by the authorities is that there is no law requiring you to talk with the police, the FBI, or the representative of any other investigative agency. Even the simplest questions may be loaded and the seemingly harmless bits of information which you volunteer may later become vital links in a chain of circumstantial evidence against you or a friend. DO NOT INVITE THE INVESTIGATOR INTO YOUR HOME! Such an invitation not only gives him the opportunity to look around for clues to your lifestyle, friends, reading material, etc., but also tends to prolong the conversation. The longer the conversation, the more chance there is for a skill investigator to find out what he wants to know. Many times a police officer will ask you to accompany him to the police station to answer a few questions. In that case, simply thank him for the invitation and indicate that you are not disposed to accept it at this time. Often the authorities simply want to photograph a person for identification purposes, a procedure which is easily accomplished by placing him in a private room with a two-way mirror at the station, asking him a few innocent questions, and then releasing him. If the investigator becomes angry at your failure to cooperate and threatens you with arrest, stand firm. He cannot legally place you under arrest or enter your home without a warr ent signed by a judge. If he indicates that he has such a warrent, ask to see it. A person under arrest, or located on premises to be searched, generally must be shown a warrent if he requests it and must be given to chance to read it. Without a warrent, an officer depends solely upon your helpfulness to obtain the information he wants. So, unless you are quite sure of yourself, don't be helpful. Probably the wisest approach to take to a persistant investigator is simply to say: "I'm quite busy now. If you have any questions that you feel I can answer, I'd be happy to listen to them in my lawyer's office. Goodbye!" Talk is cheap. When that talk involves the law enforcement authorities, it may cost you, or someone close to you, dearly. This info came from a leaflet that was printed as a public service by individuals concerned with the growing role of authoritarianism and police power in our society. Please feel free to copy or republish. This info also applies to dealing with private investigators, and corporate security agents.

Slims Table Sociology Paper essays

Slims Table Sociology Paper essays An Honest Look Into The Life Of A Working Class Black Person Slims Table, written by Mitchell Duneier has been called a true stereotype buster due to its content in which it truthfully examines the lifestyles of working class black men. The book is designed to break the common misconceptions imbedded in a majority of peoples minds over how a black man lives his life and why he in a sense does what he does, thinks what he thinks, and acts the way he acts. Prior to the writing of this book by Duneier, there were many common stereotypes of a working class black man, which often caused negative attitudes towards them. Although many of them are still existent and quiet prevalent, Duneier sought to try and break these misconceptions in hopes to try and bridge the gap, which has for so long been expanding between blacks and whites. Slims Table, appears to be written in a two-fold manner, in that Duneier tries to explain and debunk two different, yet equally important ideologies that have long since been associated to the black working class. Duneier tries to show the solidarity of the black working class with the way he presents the book, however, there is an underlying tone in which he is trying to show that the black race, in particular the struggling working class, Is in no way hopelessly wrecked by the power of white privilege or racism. He tries to debunk the unfortunate and yet demoralizing caricatures that for so long have been placed upon the heads of the black working class, with such associations as poor, uneducated, unskilled and probably the most negative of all, useless. Yet, it is the manner in which he manages to bring all of this out, which is most impressing. He remains quite unassuming and appearingly non-subjective, yet he is stating his points and supporting them all the way through the bo ok. The setting for Slims Table primarily takes place in...

Corporate Finance Essay Example | Topics and Well Written Essays - 750 words

Corporate Finance - Essay Example These are part of the benefits of registering a business as a limited liability entity. In addition to the company being an individual entity from the owners, a limited liability company offers the owners of equity capital to practice risk aversion skills. Owners of equity are not the managers of their organizations. Instead, they delegate this function to other people who they believe are capable of perfectly handling these duties. This way, the owners of equity reduce the likely of a risk of loss happening. Some investors start a business in an industry which they have little knowledge of. However, by making use of experts in that industry, they significantly reduce their risk of loss. Hired managers undertake their duties with a lot of caution, avoiding causing losses to the organization. Separation of ownership and control is a virtual necessity for the successful financing of large corporations since it leads to high performance which subsequently attracts more investors and inc reases confidence among creditors. If an organization is managed by separate persons other than the owners, due care and diligence is accorded to the organization by the management. They exhibit high levels of accountability in delivering of their duties and services towards the organization. With the knowledge that they are held accountable for any in eventualities that may arise from misrepresentation, they show care in their activities. This leads to high performance standards, which attracts more investors and shareholders in to the organization. 2. The tendency of debt ratios varies tremendously across the individual firms. However, debt ratios tend to stabilize within individual firms over a long period of time supports the pecking order model. Pecking order states that as the cost of financing increases, so does asymmetric information. Every organization gets its financing from three sources, which include internal funds, debt and equity financing. Companies therefore have to prioritize their sources of financing. Initially, organizations put into consideration their internal sources of funds. If internal funds cannot adequately meet the organization’s obligations the management considers the use of debt (Baker & Martin, 2011). However, in case this too does not help, the company might consider raising equity as measure of ‘last resort.’ Therefore, internal financing is used first, when it fails the company considers the debt, and when this does not work out, the company raises equity. This theory holds that business will conform to a hierarchy of financing resources and prefer the use of internal financing when it is available. Debt on the other hand is preferred over raising equity in case of debt financing. The extent which a company goes to in financing its operations and the type of fund chosen, the management is sure that the company will in future be in a position to repay. Mostly, internal financing is inadequate. In deciding the most appropriate form of funding between equity and debt, the organization opts for debt financing. There are two types of debt financing available, that is the short term and the long term financing. It is due to the use of debt financing that debt ratios tremendously vary across firms but tend to be stable within individual firms over long periods of time as companies repay their debts. 3. To improve a company’s profitability or popularity, many companies are either involved in hostile takeovers, mergers or

Evaluate the Relation Between the Media, Politicians and Big Donors in Essay

Evaluate the Relation Between the Media, Politicians and Big Donors in UK - Essay Example The big donors provide the huge funds for the politician’s campaigns with the aim of influencing some policies or deals when the politicians attain official or elected positions (Koss 17). With these few examples, it is apparent that there is a relationship between big donors, politicians and the media. In politics, the media has direct impact or influence on the public, as it conveys all the political messages required to sway the public in a particular direction. Therefore, for the politicians to be successful in their political bids, they have to be intertwined with the media. This is not unique for the United Kingdom, since other politicians running different affairs in other countries practice the same. The media is the main source of news for every person in the United Kingdom, therefore, making it an important tool in furthering political agendas. It influences the public immensely by swaying their perception about different politicians. The media also helps in exposing scandals that may be detrimental to some politicians’ career (Dean 12). Take the example of the United Kingdom parliamentary expenses scandal that was exposed in 2009 by the Telegraph Group. The Daily Telegraph published copies of the expenses records, which proved that members of parliament had misused the taxpayers’ money through bloated allowances and expenses. The media focused on the scandal, thus provoking anger among the citizens who demanded for the resignation and prosecution of the members of parliament involved in the scandal. The immense power of the media was demonstrated, as it was able to inform the people about secret mischievous dealings that were happening in parliament. The media was able to invoke anger in the public and create the image of a failed legislature. Owing to the media, the public lost confidence in some politicians; therefore, creating pressure for the

Protective Role of Isolated Rat Hepatocytes Against CCL4

Protective Role of Isolated Rat Hepatocytes Against CCL4 DISCUSSION CCl4, Paracetamol and Anti-tubercular drugs cause ROS mediated cellular damage especially in liver, the site of metabolism of these drugs. During the regular physiological functioning the cells/tissues/organs use oxygen and various nutrients to generate energy. The free radicals are also generated in this process as the reaction intermediates. These free radicals may be very useful because they may promote beneficial oxidative processes. However the higher quantities of such radicals like superoxide anion (O2à ¯Ã¢â‚¬Å¡Ã‚ ·), NOà ¯Ã¢â‚¬Å¡Ã‚ · radical, and hydroxyl ion radical (à ¯Ã¢â‚¬Å¡Ã‚ ·OH), NOOà ¯Ã¢â‚¬Å¡Ã‚ ·, etc. may interact with the membrane lipids leading to lipid peroxidation and attack the DNA resulting DNA strand breaks. The lipid peroxidation also damage cell membrane resulting in the leakage of enzymes into the blood stream. Therefore the elevated biochemical levels are treated as biochemical markers of tissue damage. In addition the extent of lipid peroxidation is d irectly proportional to the tissue damage [Devasagayam et al., 2003]. There are certain inbuilt protective mechanisms, tissue enzymes GSH, SOD, CAT etc. which are involved in the process of combating free radical induced tissue damage. Over powering the inbuilt protective mechanism due to excessive generation of free radicals may lead to destruction of the tissues/organs [Tiwari, 2001]. Antioxidants are the chemical constituents, which are used for inhibiting the tissue damage by countering the free radicals; most of the antioxidants available in the markets are from natural origin e.g. vit-E, vit-C, tocopherol, quercetine, à ¯Ã‚ Ã‚ ¢-carotene etc. In addition there are reports that polyphenolic compounds like flavonoids, tannins are useful as antioxidants and organ protectants. Therefore many researchers are attempting to screen the herbs and herbal preparations containing polyphenolic compounds for organ protective properties. Mruthunjaya, 2008 in his study reported the presence of very high amount of polyphenols and gallic acid, a well known potent antioxidant [Gow- chin et al, 2002] as an important constituent of the roots of a widely grown plant L. inermis. He also reported the antioxidant and in vitro and in vivo hepatoprotective activity of L. inermis root extract against CCl4 induced hepatotoxicity in rats. So in the present study L.inermis was selected f or investigating the in vivo and in vitro hepatoprotective activity against drugs induced hepatotoxicity. Before screening the test extract for in vivo hepatoprotective activity the extract was subjected to the acute toxicity studies as per OECD guidelines 425 (limit test). The LIALC was found safe up to 2000 mg/kg as evident by the absence of mortality in the treated group. Hence, 1/10th (200 mg/kg) and 1/7th (300 mg/kg) of the safe dose were selected for the in vivo study. In vitro hepatoprotective Screening In the present study, isolated rat hepatocytes were used. The objective of this study was to confirm the protective role of test extracts against CCl4 induced hepatocytes damage. The CCl4 metabolized in (liver) endoplasmic reticulum and mitochondria with the formation of CCl3O (unstable complex radical), by CYT P-450. The nascent oxygen O resulted via lipoperoxidation causes rise in intracellular reactive Fe2+ ions, aldehyde and depletion of GSH, and calcium sequestration. Oxidative CCl3O, also by direct covalent interaction induces degeneration in Ca2+ sequestration. Failure into sequestration result in increased intercellular Ca2+, aggregation by proteolytic enzymes and cause an increase in Fe2+ ions, which in turn by lipid peroxidation precipitates aldehyde cytotoxicity [Zimmerman Hayman, 1976, Agarwal et. al., 1983]. Due to this membrane integrity is lost ultimately leading to necrosis. The loss of membrane integrity can be measured by Trypan blue exclusion assay in which the viable cells exclude the dye whereas dead cell take up the dye owing to the alteration in membrane permeability. Due to loss of membrane integrity cytosolic enzymes are leaked into media and the measurement of these cytoplasmic enzymes in the media serves as ideal markers for evaluating the extent of hepatocyte injury and protection offered by extracts. From the results it was apparent that both LIALC and LIAQ protect the hepatocytes against CCl4 damage as evident by the reversal of cell death and inhibition leakage of cytosolic enzymes. As discussed earlier this strong hepatoprotective activity of LIALC might be due presence of polyphenols and gallic acid which are potent free radical scavenging agents and antioxidants [Gow- chin et al, 2002] In vivo hepatoprotective activity Paracetamol (N-acetyl-p-aminophenol) is a widely used analgesic and antipyretic drug and is safe when used in therapeutic doses. However over dosage of Paracetamol is known to be hepatotoxic and nephrotoxic in man and in experimental animals [Parmar et al., 1995]. Paracetamol is a direct hepatotoxin i.e. intoxication is dose dependent and reproducible [Tygstrup et al., 1996]. Exposure of animals to higher doses produces centrilobular or massive hepatic necrosis followed by congestion and failure. The hepatic necrosis is associated with damage to sub cellular organelle including mitochondria. Thus the drug is used as a typical hepatotoxin to produce hepatic failure experimentally [Sing et al., 1999]. At lower doses, about 80% of ingested Paracetamol is eliminated mainly as sulfate and glucoronide conjugates before oxidation and only 5% is oxidized by hepatic CYT P450(CYP2E1) to a highly reactive and toxic electrophile i.e. N-acetyl-p-benzoquineimine (NAPQI). After over dosage of Paracetamol the glucoronidation and sulfation routes become saturated and as a consequence, Paracetamol is increasingly metabolized into NAPQI [Remirez et al., 1995]. Semiquinone radical, one-electron reduction metabolite of NAPQI mediates the cytotoxic effects of NAPQI. Production of these toxic semiquinone radicals is catalyzed by the microsomal CYT P450 reductase. These semiquinone radicals, in turn, can bind directly with cellular macromolecules to produce toxicity or alternatively, the radical can be reoxidized back to their original quinones by donating one electron to molecular oxygen under aerobic conditions. This donation of one electron then generates reduced oxygen radical species and hydroxyl radical. Both semiquinone and oxygen radical are known to be responsible for cytotoxic effects observed with quinones. Also NAPQI is detoxified by glutathione (GSH) to form 3-(GSH-S-yl) acetaminophen. Paracetamol overdose saturates the nontoxic metabolic pathway, i.e. sulfation, glucuronidation, and detoxification of NAPQI by glutathione. The reactive NAPQI may oxidize and arylate cysteinyl thiol group, forming adducts which inhibit the function of cellular proteins. Adducts formation has been demonstrated for a selenium-binding protein, for microsomal subunit of glutamine. Other mechanism, such as oxidation of pyridine nucleotides and lipid peroxidation, may contribute to cell damage by Paracetamol overdose [Tygstrup et al., 1996]. Nevertheless at high doses of Paracetamol, NAPQI can alkylate and oxidize intracellular GSH and protein thiol group, which result in the liver GSH pool depletion and the reactive intermediate reacts with other nucleophilic centers of vital molecules in liver cells leading subsequently to hepatotoxicity. In addition Paracetamol is also shown to directly inhibit cellular proliferation, induce oxidative stress, resulting in lipid peroxidation, deplete ATP levels and alter Ca++ homeostasis; all of these changes are considered potentially fatal to the cell [Sing,. 1999 and Remirez et al., 1995]. Anti-tuberculosis drugs act as inducers of hepatic CYT P450 enzymes. For example, Rifampicin is a potent inducer of CYP2D6 and CYP3A4, and Isoniazid induces CYP2E1 [Trevor, 2004 and Vuilleumier et al., 2006]. The induction of CYT P450 enzymes is known to take part in increased drug disposition and development of multi-drug resistance. Xenobiotics, including anti-tubercular drugs, undergo biotransformation in the liver catalyzed by microsomal enzyme systems [Bradford, 2005; Dai et al., 1995and Jeong, 1995]. Because of above reasons, Paracetamol and anti-tubercular drugs cause ROS mediated hepatotoxicity and elevate serum enzymes levels like SGOT, SGPT, ALP, LDH and Bilirubin content in animals following administration of anti-tubercular drugs or toxic dose of Paracetamol. Also these drugs cause depletion of endogenous antioxidant enzymes like GSH, SOD, CAT etc and abnormal levels of lipid peroxidation products.The results obtained in the present are in accordance with understanding as discussed above. i.e the serum enzymes levels like SGOT, SGPT, ALP, LDH and Bilirubin contents were significantly increased, GSH, SOD, CAT levels in liver depleted and abnormal levels of lipid peroxidation was observed in Paracetamol and anti-tubercular drugs treated animals. Estimation of serum enzymes SGPT is a cytosolic enzyme primarily present in the liver. The level of SGPT in serum increases due to leakage of this cellular enzyme into plasma by hepatic injury [Chenoweth Hake, 1962]. Serum levels of SGPT can increase due to damage of the tissues producing acute hepatic necrosis, such as viral hepatitis and acute cholestasis. Alcoholic liver damage and cirrhosis also can associate with mild to moderate elevation of transaminase [Harsh Mohan, 2002]. SGOT is a mitochondrial enzyme released from heart, liver, skeletal muscle and kidney. Liver toxicity elevated the SGOT level in serum due to the damage to the tissues producing acute necrosis, such as severe viral hepatitis acute cholestasis. Alcoholic liver damage and cirrhosis can also associate with mild to moderate elevation of transaminases [Harsh Mohan, 2002]. In case of toxic liver, ALP levels are very high, which may be due to defective hepatic excretion or by increased production of ALP by hepatic parenchymal or duct cells [Harsh Mohan, 2002]. LIALC reversed these enzyme levels indicating stabilization of cell membrane by preventing the damage due to free radicals generated by Paracetamol and anti-tubercular drugs. Estimation of bilirubin: In case of toxic liver, bilirubin levels are elevated. Hyperbilirubinemia can result from impaired hepatic uptake of unconjugated bilirubin. Such a situation can occur in generalized liver cell injury. Certain drugs (e.g., Rifampin and Probenecid) interfere with the net uptake of bilirubin by the liver cell and may produce a mild unconjugated hyperbilirubinemia [Rubin, 1995]. Bilirubin level rises in diseases of hepatocytes, obstruction to biliary excretion into duodenum, in haemolysis and defects of hepatic uptake and conjugation of bilirubin pigment such as in Gilbert’s disease [Harsh mohan, 2002]. Significant reversal of elevated bilirubin level in Paracetamol and anti-tubercular drug treated animals by LIALC indicated the strong hepatoprotective activity of LIALC. Estimation of Protein A reduction in total serum protein observed in the Paracetamol and anti-tubercular treated control rats may be associated with the decrease in the number of hepatocytes which in turn might result in decreased hepatic capacity to synthesize protein. But, when the LIALC was administered along with Paracetamol or anti-tubercular drugs a significant increase in protein content was observed indicating the hepatoprotection of LIALC. Estimation of endogenous antioxidant enzymes and Lipid Peroxidation Cells have a number of mechanisms to protect themselves from the toxic effects of the ROS. SOD removes superoxide (O2) by converting it to H2O2, which can be rapidly converted to water by CAT and Glutathione peroxidase. In addition, a large reserve of reduced glutathione is present in hepatocytes and red blood cells for detoxification of xenobiotics or free radicals. However, oxidative stress results in toxicity when the rate of which the ROS are generated exceeds the cell capacity for their removal. Lipid peroxidation is an autocatalytic process, which is a common consequence of cell death. This process may cause peroxidative tissue damage in inflammation, cancer and toxicity of xenobiotics and aging. MDA is one of the end products in the lipid peroxidation process. In order to elucidate the protection mechanism of LIALC in Paracetamol and anti- tubercular Drugs induced rat liver, lipid peroxide levels and anti-oxidative enzymes activities were analyzed. GSH is widely distributed in cells. GSH is an intracellular reductant and plays a major role in catalysis, metabolism and transport. It protects cells against free radicals, peroxides and other toxic compounds. GSH is a naturally occurring substance that is abundant in many living creatures. It is well known that a deficiency of GSH within living organisms can lead to tissue disorders and injury. For example, liver injury included by consuming alcohol or by taking drugs like Paracetamol, lung injury by smoking and muscle injury by intense physical activity, all are known to be correlated with low tissue level of GSH. The SOD converts super-oxide radicals (O2_) into H2O2 plus O2, thus participating in the enzymatic defense against oxygen toxicity. In this study, SOD plays an important role in the elimination of ROS derived from the peroxidative process of xenobiotics in liver tissues. CAT is the key component of the anti-oxidant defense system .Inhibition of this protective mechanisms result in enhanced sensitivity to free radical induced cellular damage. Administration of LIALC increased the activity of catalase in Paracetamol and anti-tubercular drug induced liver damage to prevent the accumulation of excessive free radicals and thus exhibited protection against Paracetamol and anti-tubercular drug. The observed increase of SOD, CAT and GSH activity in liver suggests that the LIALC extract have an efficient protective mechanism in response to ROS. And also, these findings indicate that LIALC may be associated with decreased oxidative stress and free radical mediated tissue damage. In our study, elevation in the levels of end products of lipid peroxidation in liver of rat treated with Paracetamol and anti- tubercular drugs were observed. The increase in MDA level in liver suggests enhanced lipid peroxidation leading to tissue damage and failure of anti-oxidant defense mechanism to prevent formation of excessive free radicals. Treatment with LIALC significantly reversed these changes. Hence it may be possible that the mechanism of hepatoprotection of LIALC is due to its antioxidant effect. Dept of pharmacology, P.R.R.M college of pharmacy,kadapaPage 1

The poem Two Scavengers in a Truck, Two Beautiful People in a Mercedes

The poem Two Scavengers in a Truck, Two Beautiful People in a Mercedes is a descriptive poem by Lawrence Ferlinghetti. Night of the Scorpion & Two Scavengers in a Truck, Two Beautiful People in a Mercedes The poem Two Scavengers in a Truck, Two Beautiful People in a Mercedes is a descriptive poem where the poet (Lawrence Ferlinghetti) observes two garbage men in San Francisco and two well-paid people in a Mercedes. The poet's observation is really about the way the garbage men look at the well-paid people and the way the rich people look at the garbage men when waiting at the traffic lights. This poem is about two garbage men and two posh office people in the Mercedes who stop at the same traffic light at the same time on the same day. The main reason I enjoyed this poem was because of the description of each person in the poem. One description I really liked was the description of the two people in the Mercedes, '' The man in the hip three-piece linen suit with shoulder-length blond hair & sunglasses The young blond women so casually coifed with a short skirt...